An alarming decrease in crop production from heat exposure is becoming a mounting threat to food security worldwide. The Intergovernmental Panel on Climate Change (IPCC) projects that global wheat yields could decline by 6-10% for every 1°C temperature increase. Heat waves pose even graver threats, reducing harvests by 15–30% and farm incomes by a staggering 66%.
ThermoReLEAF claims that its innovative platform that combines gene editing technology and biomolecule discovery can offer a solution to bolster crop resilience to heat stress by enhancing plant tolerance. Using specific gene editing and biomolecules derived from plants, it says it can help to stabilize yields, safeguard farmer revenues, and help to secure food systems globally.
The problem it addresses is pressing. High temperatures during critical crop growth phases—such as flowering and grain filling—can cause irreversible damage. The repercussions of these losses are felt worldwide; in 2022, heatwaves in India and Pakistan reduced wheat yields by up to 30%, prompting export bans. Europe and North America have faced significant crop destruction due to soaring temperatures, which has decreased food supplies and driven up prices.
Heatwaves also jeopardize seed quality, shorten the growing season, and raise the risk of complete crop failures. As these heat events grow more frequent and severe, the challenge to crop productivity—and consequently food availability—is anticipated to escalate further.
After extensive research, ThermoReLEAF says that it has identified a novel solution to these challenges. According to the initiative, it has discovered the precise molecular mechanism that causes heat-induced cell death in plants. The team claims to have disrupted this process without hampering plant growth or development, creating heat-resistant crops ready to weather soaring temperatures. Its CRISPR-Cas9 technology executes precise genetic edits to knock out specific genes.

Recognizing the existing regulatory hurdles around gene editing, especially in regions already grappling with heat-related losses, ThermoReLEAF has also unveiled an environmentally friendly biochemical solution composed of plant-derived biomolecules. When applied to seeds or leaves, the initiative explains that the product targets the same harmful molecular pathway as the gene editing approach, which enhances crop survival and productivity under heat stress in all tested varieties.
The initiative says that the technology’s versatility means that it can be applied across a broad spectrum of crop species, ranging from cereals to vegetables and legumes. This could ensure that a wide array of agricultural products is shielded from the perils of heat stress. ThermoReLEAF believes this universal applicability could help to secure the immediate food supply and sustain the livelihoods of farmers and communities in some of the most vulnerable countries in the world.
Learn more about ThermoReLEAF.
Written by Gilly Smith
Photos provided by ThermoReLEAF

















